Basic Laboratory Research

Back in the 1800's, respiratory disease was the number one reason for illness and death worldwide.  But, the reason "why" was unknown until the development of laboratory-based medicine became a reality around the mid-1800's.  Through laboratory research, it was possible to test ideas and validate theories related to causes of respiratory disease and to begin diagnosing clinical disease and developing specific therapies or cures. 

It was in 1877 that Robert Koch, M.D. was able to show that a specific micro-organism could cause disease.  Within five years, he discovered the cause of tuberculosis, a specific bacterial micro-organism which was causing illness and death around the globe.   By 1890, Emil Von Behring, M.D. developed the first therapy that provided a cure for disease (an anti-toxin to diptheria, a deadly respiratory  disease that was widespread among children).  Each of these pioneers in laboratory medicine received the Nobel Prize in Medicine for their important discoveries that ultimately saved millions of lives worldwide. 

The average life expectancy since the middle of the 19th century has nearly doubled, in large part due to the prevention and irradication of infectious pulmonary disease.  However, as people are living longer, we are being confronted with new medical conditions and challenges in the present era.   Today, basic science and laboratory medicine remains at the core of new discoveries that can significantly impact modern medical practice, save lives and improve health-related quality of life for those with lung-related disease and breathing disorders.